Curriculum Vitae
CV:Xuexing Zheng
Born 1983-05-25
· Higher education qualification: BS 2006,Veterinary Medicine, Jilin University.
· Degree of Doctor:
Year:2011,
Discipline/Subject area: Virology / Veterinary Medicine,
Dissertation title: Mechanisms of HIV-related neuropathy.
Supervisor: Professor Xianzhu Xia
· Postdoctoral positions:
Department of Microbiology, Faculty of The Biotechnology Research Institute, CAAS. 2012-2015
· Present position:
Associate professor, Microbiology, Faculty of College of Public Health, University of Shandong, 2015-
· Other information of relevance to the application
· Research projects of agricultural public welfare industry in China (2013-2017): Rapid diagnosis and vaccine research of pet disease.Xuexing Zheng is Co-PI in the subproject, focuses on the epidemiology, propagation dynamics, rapid diagnostics, and novel vaccines for pet bacterial and viral diseases. A pet epidemiological monitoring network centered on pet hospitals was established. Established canine distemper virus and canine parvovirus sample preservation and transportation standards, clinical diagnostic criteria, laboratory diagnostic criteria.
· National Natural Science Foundation of China (2015-2017): The roles and regulatory mechanism of autophagy in rabies virus infection
· National Key R&D Program of China (2016-2020): Pet disease diagnosis, treatment, and prevention. Xuexing Zheng is Co-PI in the subproject, focuses on the pet as a vector-borne bacterial disease.
l Partially publications
[1] C Wang#,X Zheng#, W Gai, G Wong, H Wang, H Jin, N Feng, Y Zhao, W Zhang, N Li, G Zhao, J Li, J Yan, Y Gao, G Hu, S Yang, X Xia. Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain induce specific humoral and cellular immune response in mice. Antiviral Res. 2017;140:55-61.
[2] W Gai#,X Zheng#, C Wang#, H Wang, Y Zhao, Q Wang, G Wong, W Zhang, N Feng, B Qiu, H Chi, N Li, T Wang, Y Gao, J Shan, S Yang, X Xia. Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice. Virol J. 2017;14:204.
[3] W Gai, W Zheng, C Wang, G Wong, Y Song,X Zheng*. Immunization with recombinant rabies virus expressing Interleukin-18 exhibits enhanced immunogenicity and protection in mice. Oncotarget. 2017;8:91505-15.
[4]X Zheng#, G Wong#, Y Zhao#, H Wang, S He, Y Bi, W Chen, H Jin, W Gai, D Chu, Z Cao, C Wang, Q Fan, H Chi, Y Gao, T Wang, N Feng, F Yan, G Huang, Y Zheng, N Li, Y Li, J Qian, Y Zou, G Kobinger, G F Gao, X Qiu, S Yang, X Xia. Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection. Scientific reports. 2016;6:24179.
[5]X Zheng, S Wang, W Zhang, X Liu, Y Yi, S Yang, X Xia, Y Li, Z Zhang. Development of a VLP-based vaccine in silkworm pupae against rabbit hemorrhagic disease virus. Int Immunopharmacol. 2016;40:164-9.
[6] X H Xue#,X X Zheng#, H L Wang, J Z Ma, L Li, W W Gai, T C Wang, S T Yang, X Z Xia. An inactivated recombinant rabies CVS-11 virus expressing two copies of the glycoprotein elicits a higher level of neutralizing antibodies and provides better protection in mice. Virus Genes. 2014.
[7] X Xue#,X Zheng#, H Liang, N Feng, Y Zhao, Y Gao, H Wang, S Yang, X Xia. Generation of recombinant rabies Virus CVS-11 expressing eGFP applied to the rapid virus neutralization test. Viruses. 2014;6:1578-89.
[8]X Zheng, W Zheng, S Liu, H M Patel, X Xia, H Ouyang, R C Levitt, K A Candiotti, S Hao. Crosstalk between JNK and NF-kappaB in the KDO2-mediated production of TNFalpha in HAPI cells. Cell Mol Neurobiol. 2012;32:1375-83.
[9] W Zheng#,X Zheng#, S Liu, H Ouyang, R C Levitt, K A Candiotti, S Hao. TNFalpha and IL-1beta are mediated by both TLR4 and Nod1 pathways in the cultured HAPI cells stimulated by LPS. Biochem Biophys Res Commun. 2012;420:762-7.
[10]X Zheng, H Ouyang, S Liu, M Mata, D J Fink, S Hao. TNFα is involved in neuropathic pain induced by nucleoside reverse transcriptase inhibitor in rats. Brain, behavior, and immunity. 2011;25:1668-76.
